Damage to your blood vessels causes them to swell and bleed. Tissue deposits of igabinding streptococcal m proteins in iga. The streptococcal igabinding peptides sap, designated sap4, sap22, and. The most striking feature of this form of vasculitis is a purplish rash, typically on the lower legs and buttocks. Hsp most commonly affects the blood vessels in your skin, joints, intestines, and kidneys. Henochschonlein purpura hsp is an acute immunoglobulin a igamediated disorder characterized by a generalized vasculitis involving. Henochschonlein purpura hsp is a disease that causes small blood vessels to become inflamed and leak blood. Henochschonlein purpura when blood vessels get inflamed, they can bleed into the skin, causing a reddishpurple rash purpura. The patient in this video presented to the emergency department with henochschonlein purpura hsp and his mother, a cnra, agreed to allow us to. What is the role of iga in the pathophysiology of henochschonlein. Hemorragia pulmonar, una complicacion poco frecuente en una. Henochschonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels. Hsp can happen at any age but is most common in children 2 to 11 years of age.
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